2021年04月18日发布 | 1993阅读

图解MCA夹层DSA表现和脑梗死机制

陈红兵

中山大学附属第一医院

达人收藏



根据文献,颅内动脉夹层脑梗死机制包括:

J.Y. Kwon, et al., Intracranial and extracranial arterial dissection spansenting with ischemic stroke: Lesion location and stroke mechanism, J Neurol Sci (2015), http://dx.doi.org/10.1016/j.jns.2015.09.368


1动脉-动脉栓塞:DWI显示动脉夹层病变以远供血区小梗死灶;这些梗死灶一般体积小、多发、散在分布,通常与夹层动脉供血区灌注障碍相关联(笔者注:血栓清除能力降低)。

Artery-to-artery embolism: DWI shows small infarcts distal to the dissected vessel in the territory of the relevant artery. The infarct lesions are usually small, multiple, and scattered, and are often associated with perfusion deficits in the territory of the dissected vessel.


2闭塞穿支动脉:梗死灶临近动脉夹层病变,考虑是夹层局部血栓形成闭塞了一条或多条穿支动脉开口。

Local branch occlusion: The infarct is localized to the area adjacent to the dissected vessel, spansumably because the orifice of one or more of the small perforators supplying the regions is occluded by local thrombus formation.


3原位血栓闭塞:临近夹层病变的相对管径较大血管因血栓形成(管腔闭塞或严重狭窄)造成其供血区梗死,通常是连续的大范围梗死,可能一些区域因侧支循环建立而得以保留。

In situ thrombotic occlusion: The territorial infarction is caused by a relatively large artery occlusion or severe stenosis resulting from thrombus formation adjacent to the dissected vessel. Usually the lesions are confluent and large, but some portions may be spanserved due to the development of collateral vessels.


4血流动力学障碍:DWI显示的梗死灶位于分水岭区,一般呈线样分布,与管腔严重狭窄或闭塞(夹层病变所致)下游灌注衰竭相关。

Hemodynamic impairment: The DWI-identified infarcts are located in border zone areas, usually linear in shape, and are associated with perfusion deficitsdistal to the severely stenosed or occluded vessel.




大脑中动脉夹层案例实践


0
1
案例


闭塞穿支动脉

男,57岁



△DSA:左侧大脑中动脉主干中部内膜征和夹层假腔(红箭),主干远段严重狭窄(黄箭)。



△FLAIR:左侧大脑中动脉主干远段走形区条状等高信号(红箭,壁内血肿可能)。



FLAIR:左侧壳核后部梗死(外侧豆纹动脉供血)。



0
2
案例


血流动力学障碍

男,65岁



△DSA:左侧大脑中动脉上干局部内膜征(红箭)。



△DWI:左侧内部分水岭梗死。


0
3
案例


混合机制:闭塞穿支动脉+血流动力学障碍

男,65岁




△二维和三维DSA:右侧大脑中动脉主干局部内膜征(红箭),伴管腔严重狭窄。




DWI:右侧基底节区和内部分水岭梗死。



0
4
案例


混合机制:闭塞穿支动脉+动脉-动脉栓塞

男,7岁




△二维和三维DSA:左侧颈内动脉颅内段和大脑中动脉主干长段不规则狭窄,左侧大脑中动脉主干局部可见内膜征(红箭)。



DWI:左侧基底节区、岛叶和额叶多发梗死。


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